Desquamative interstitial pneumonitis in a patient with systemic lupus erythematosus

Can Respir J. 2012 Jan-Feb;19(1):50-2. doi: 10.1155/2012/129403.


Desquamative interstitial pneumonia (DIP) is a rare form of interstitial lung disease (ILD) commonly found among healthy smokers. ILD is a rare manifestation of systemic lupus erythematosus (SLE), and typically associated with a histopathological pattern of nonspecific interstitial pneumonia (NSIP). The present article describes an unusual case of DIP in a nonsmoking patient with SLE presenting as NSIP. DIP can occur in the context of SLE in patients with a negative smoking history, and clinicians should consider lung biopsy to correctly classify ILD with unusual presentation on computed tomography scan.

La pneumonite interstitielle desquamative (PID) est une forme rare de maladie pulmonaire interstitielle (MPI), souvent observee chez les fumeurs en bonne sante. La MPI est une rare manifestation de lupus erythemateux dissemine (LED), et elle s’associe generalement a un profil histopathologique de pneumonie interstitielle non specifique(PINS). Le present article decrit un cas inhabituel de PID chez un patient qui n’avait jamais fume et qui avait un LED se presentant sous forme de PINS. La PID peut se manifester en cas de LED chez les patients n’ayant jamais fume, et les cliniciens devraient envisager une biopsie pulmonaire pour bien classer la MPI ayant une presentation inhabituelle a la tomodensitometrie.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use
  • Biopsy
  • Humans
  • Lung / diagnostic imaging
  • Lung / pathology*
  • Lung Diseases, Interstitial / diagnosis*
  • Lung Diseases, Interstitial / drug therapy
  • Lung Diseases, Interstitial / etiology
  • Lupus Erythematosus, Systemic / complications*
  • Male
  • Prednisone / therapeutic use
  • Tomography, X-Ray Computed
  • Young Adult


  • Anti-Inflammatory Agents
  • Prednisone