Downregulation of monocyte chemoattractant protein 1 expression by prostaglandin E(2) in human ocular surface epithelium

Arch Ophthalmol. 2012 Feb;130(2):249-51. doi: 10.1001/archopthalmol.2011.1472.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chemokine CCL2 / genetics*
  • Chemokine CCL2 / metabolism
  • Conjunctiva / cytology
  • Conjunctiva / drug effects*
  • Conjunctiva / metabolism
  • Dinoprostone / analogs & derivatives
  • Dinoprostone / pharmacology*
  • Down-Regulation / physiology*
  • Enzyme-Linked Immunosorbent Assay
  • Epithelial Cells / drug effects
  • Epithelial Cells / metabolism
  • Humans
  • Limbus Corneae / cytology
  • Limbus Corneae / drug effects*
  • Limbus Corneae / metabolism
  • Poly I-C / antagonists & inhibitors
  • Poly I-C / pharmacology
  • RNA, Messenger / metabolism
  • Real-Time Polymerase Chain Reaction
  • Receptors, Prostaglandin E, EP2 Subtype / metabolism
  • Receptors, Prostaglandin E, EP3 Subtype / metabolism

Substances

  • 9-deoxy-9-chloro-15-deoxy-16-hydroxy-17,17-trimethylene-19,20-didehydroprostaglandin E2
  • CCL2 protein, human
  • Chemokine CCL2
  • ONO AE 248
  • PTGER2 protein, human
  • PTGER3 protein, human
  • RNA, Messenger
  • Receptors, Prostaglandin E, EP2 Subtype
  • Receptors, Prostaglandin E, EP3 Subtype
  • Dinoprostone
  • Poly I-C