Meta-analysis of navigation vs conventional total knee arthroplasty

J Arthroplasty. 2012 Jun;27(6):1177-82. doi: 10.1016/j.arth.2011.12.028. Epub 2012 Feb 13.


Navigated total knee arthroplasty (TKA) is promoted as a means to improve limb and prosthesis alignment. This study involved a systematic review and meta-analysis for all randomized controlled trials in the literature from 1986 to 2009 comparing alignment outcomes between navigated and conventional TKA. Alignment outcomes were pooled using a random-effects model, and heterogeneity was explored. Twenty-three randomized controlled trials were identified comparing navigated vs conventional TKA involving 2541 patients. Patients who underwent navigated TKA had a significantly lower risk of implant malalignment at more than 3° as well as more than 2°. In addition, the risk of malalignment was reduced for the coronal plane tibial and femoral components as well as femoral and tibial slope. This meta-analysis demonstrates that navigated TKA provides significant improvement in prosthesis alignment.

Publication types

  • Comparative Study
  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Arthroplasty, Replacement, Knee / instrumentation
  • Arthroplasty, Replacement, Knee / methods*
  • Biomechanical Phenomena
  • Bone Malalignment / epidemiology
  • Bone Malalignment / prevention & control*
  • Humans
  • Knee Joint / physiology
  • Knee Prosthesis / adverse effects*
  • Risk Factors
  • Surgery, Computer-Assisted / methods*