First case report of an acute genotype 3 hepatitis E infected pregnant woman living in South-Eastern France

J Clin Virol. 2012 May;54(1):76-8. doi: 10.1016/j.jcv.2012.01.016. Epub 2012 Feb 14.


In European countries, epidemiology of hepatitis E virus (HEV) infection is not well known. Although, seroprevalence of HEV Immunoglobulin G reached a few percent in European women, no acute hepatitis E during pregnancy has been described so far. Here, we report a case of an autochthonous HEV genotype 3 infection in a 41-years-old pregnant woman living in a non-endemic country. The acute hepatitis had a spontaneous good outcome for the mother and the child. In non-endemic areas where Hepatitis E infections are emerging, unexplained cytolysis, whatever its level, in a pregnant woman could be investigated for HEV, using biological molecular and serology tools.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • France
  • Genotype
  • Hepatitis E / diagnosis*
  • Hepatitis E virus / classification
  • Hepatitis E virus / genetics
  • Hepatitis E virus / isolation & purification*
  • Humans
  • Infant
  • Infant, Newborn
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis*
  • RNA, Viral / genetics*
  • Treatment Outcome


  • RNA, Viral