Comparison of prediction error: labeled versus unlabeled intraocular lens manufacturing tolerance

J Cataract Refract Surg. 2012 Mar;38(3):394-402. doi: 10.1016/j.jcrs.2011.08.044.

Abstract

Purpose: To compare the prediction error between intraocular lenses (IOLs) available in 0.25 diopter (D) increments with a labeled manufacturing tolerance and IOLs available in 0.50 D increments without a labeled manufacturing tolerance.

Setting: Community-based multidisciplinary outpatient ophthalmic practices.

Design: Comparative case series.

Methods: Eyes with cataract had implantation of an IOL available in 0.25 D increments and labeled with a manufacturing tolerance of ± 0.11 D (labeled group) or an IOL available in 0.50 D increments without a labeled manufacturing tolerance (unlabeled group). Postoperatively, the prediction error was calculated and compared between groups.

Results: By the SRK/T formula, the mean error of prediction after optimization was -0.03 D ± 0.35 (SD) in the labeled group and -0.05 ± 0.46 D in the unlabeled group (P=.64). The mean absolute error of prediction was statistically significantly smaller in the labeled group (0.26 ± 0.23 D) than in the unlabeled group (0.37 ± 0.28 D) (P=.04). The mean and absolute errors were not statistically significantly different with the Holladay 1 or Hoffer Q formula. Sixty-three percent of patients in the labeled group and 43% in the unlabeled group (P=.03) were within ± 0.25 D of the prediction error; 84% and 69%, respectively, were within ± 0.50 D (P=.06).

Conclusion: The IOLs available in 0.25 D increments with a labeled manufacturing tolerance of ± 0.11 D increased the percentage of patients within ± 0.25 D of the targeted refraction to a statistically significant and clinically meaningful level compared with unlabeled IOLs available in 0.50 D increments.

Financial disclosure: No author has a financial or proprietary interest in any material or method mentioned.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Biometry
  • Cataract / complications*
  • Female
  • Humans
  • Lens Implantation, Intraocular*
  • Lenses, Intraocular / standards*
  • Male
  • Manufactured Materials
  • Middle Aged
  • Optics and Photonics*
  • Phacoemulsification*
  • Refraction, Ocular / physiology*
  • Visual Acuity / physiology*