Commercialization of microfluidic point-of-care diagnostic devices

Lab Chip. 2012 Jun 21;12(12):2118-34. doi: 10.1039/c2lc21204h. Epub 2012 Feb 17.


A large part of the excitement behind microfluidics is in its potential for producing practical devices, but surprisingly few lab-on-a-chip based technologies have been successfully introduced into the market. Here, we review current work in commercializing microfluidic technologies, with a focus on point-of-care diagnostics applications. We will also identify challenges to commercialization, including lessons drawn from our experience in Claros Diagnostics. Moving forward, we discuss the need to strike a balance between achieving real-world impact with integrated devices versus design of novel single microfluidic components.

Publication types

  • Review

MeSH terms

  • DNA / analysis
  • Government Regulation
  • HIV Infections / diagnosis
  • Humans
  • Immunoassay
  • Industry
  • Microfluidic Analytical Techniques / economics
  • Microfluidic Analytical Techniques / instrumentation*
  • Microfluidic Analytical Techniques / methods
  • Point-of-Care Systems* / economics
  • T-Lymphocytes / cytology
  • T-Lymphocytes / metabolism


  • DNA