[Molecular cloning of Tupaia belangeri chinensis neuropeptide Y and homology comparison with other analogues from primates]

Dongwuxue Yanjiu. 2012 Feb;33(1):75-8. doi: 10.3724/SP.J.1141.2012.01075.
[Article in Chinese]


Much attention has been payed to tree shrews for their close phylogenetic relationship with primates, small size, and short reproductive cycle. Especially, they are considered as excellent experiential animals for medicine or/and disease research. A nucleotide sequence encoding neuropeptide Y(NPY) precursor has been cloned from the cDNA library of Tupaia belangeri chinensis. Sequence alignment revealed that the sequence homology with primate NPY was up to 96.9%. The phylogenetic analysis based on NPY precursor sequence revealed that the tree shrew has a close relationship with primates.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cloning, Molecular
  • Humans
  • Models, Molecular
  • Molecular Sequence Data
  • Neuropeptide Y / chemistry
  • Neuropeptide Y / genetics*
  • Phylogeny
  • Primates / classification
  • Primates / genetics*
  • Sequence Alignment
  • Tupaia / classification
  • Tupaia / genetics*


  • Neuropeptide Y