K/BxN serum transfer arthritis as a model of inflammatory joint pain

Methods Mol Biol. 2012;851:249-60. doi: 10.1007/978-1-61779-561-9_19.

Abstract

In this chapter, we describe the usage of this rheumatoid arthritis model to investigate pain-like behavior in mice, including the assessment of clinical changes and the time-dependent changes in nociceptive behavior during disease progresses.

MeSH terms

  • Animals
  • Arthralgia / immunology
  • Arthralgia / physiopathology*
  • Arthritis, Rheumatoid / immunology
  • Arthritis, Rheumatoid / physiopathology*
  • Autoantibodies / blood*
  • Behavior, Animal
  • Disease Models, Animal*
  • Inflammation / immunology
  • Inflammation / physiopathology
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, Transgenic
  • Receptors, Antigen, T-Cell / genetics
  • Receptors, Antigen, T-Cell / metabolism

Substances

  • Autoantibodies
  • Receptors, Antigen, T-Cell