National Institutes of Health State-of-the-Science Conference: role of active surveillance in the management of men with localized prostate cancer

Ann Intern Med. 2012 Apr 17;156(8):591-5. doi: 10.7326/0003-4819-156-8-201204170-00401. Epub 2012 Feb 20.


National Institutes of Health (NIH) Consensus and State-of-the-Science Statements are prepared by independent panels of health professionals and public representatives on the basis of 1) the results of a systematic literature review prepared under contract with the Agency for Healthcare Research and Quality, 2) presentations by investigators working in areas relevant to the conference questions during a 2-day public session, 3) questions and statements from conference attendees during open discussion periods that are part of the public session, and 4) closed deliberations by the panel during the remainder of the second day and morning of the third. This statement is an independent report of the panel and is not a policy statement of NIH or the U.S. government.

The statement reflects the panel’s assessment of medical knowledge available at the time the statement was written. Thus, it provides a “snapshot in time” of the state of knowledge on the conference topic. When reading the statement, keep in mind that new knowledge is inevitably accumulating through medical research. The following statement is an abridged version of the panel’s report, which is available in full at

Publication types

  • Consensus Development Conference, NIH

MeSH terms

  • Biopsy
  • Comparative Effectiveness Research
  • Digital Rectal Examination
  • Disease Progression
  • Humans
  • Male
  • Neoplasm Grading
  • Neoplasm Staging
  • Patient Acceptance of Health Care
  • Patient Selection
  • Prostate-Specific Antigen / blood
  • Prostatic Neoplasms / diagnosis*
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / therapy*
  • Risk Factors
  • Watchful Waiting*


  • Prostate-Specific Antigen