Treatment of catatonia with amantadine

Clin Neuropharmacol. Mar-Apr 2012;35(2):86-7. doi: 10.1097/WNF.0b013e318246ad34.


Catatonia is an episodic syndrome characterized by specific affective, behavioral, and motor symptoms and thought to result from regional abnormalities in neurotransmitter function. Although generally thought to represent a manifestation of schizophrenia or depression, there is strong evidence that it may represent a distinct entity, caused by a number of psychogenic, infectious, iatrogenic, and neurological conditions. The morbidity associated with catatonia is significant, and, in some cases, the condition may be life threatening.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Amantadine / therapeutic use*
  • Catatonia / complications
  • Catatonia / drug therapy*
  • Catatonia / psychology
  • Humans
  • Male
  • Schizophrenia / complications
  • Schizophrenia / drug therapy*
  • Treatment Outcome


  • Amantadine