Cell biology: Collagen secretion explained

Nature. 2012 Feb 22;482(7386):474-5. doi: 10.1038/482474a.


Cells package proteins into vesicles for secretion to the extracellular milieu. A study shows that an enzyme modifies the packaging machinery to encapsulate unusually large proteins such as collagen.

Publication types

  • News
  • Comment

MeSH terms

  • Animals
  • COP-Coated Vesicles / chemistry*
  • COP-Coated Vesicles / metabolism*
  • Humans
  • Ubiquitin / metabolism*


  • Ubiquitin