We investigated the feasibility and accuracy of using Internet-based videoconferencing for double-checking medications. Ten participants checked 30 different medications using a desktop PC and a webcam. The accuracy of the video-based checks was compared with 'face-to-vial' checks. The checks included the drug name, dosage and expiry dates of ampoules, vials and tablets, as well as graduations on syringes. There was 100% accuracy for drug name, dosage, and graduations on syringes greater than 1 unit. The expiry dates proved more difficult to read, and accuracy was only 63%. The mean overall accuracy was 91% for all items. Internet video-based medication double-checks may have a useful role to play in processes to ensure the safe use of medications in home care.