A comparison of two clinical methods for measuring saliva in patients with Sjögren's syndrome

Acta Odontol Scand. 2012 May;70(3):251-4. doi: 10.3109/00016357.2011.640285. Epub 2012 Feb 27.


Objective: The aim of the present study was to evaluate two different ways of measuring unstimulated and stimulated whole salivary output in the dental clinic, namely by volume (mL/min) and by weight (g/min).

Materials and methods: Thirty-one patients diagnosed with Secondary Sjögren's syndrome (SSS) participated in the study.

Results: The results showed a large discrepancy between the measurements performed by volume and by weight (p < 0.001) and additionally when taking into account density calculation, especially in individuals with low salivary secretion rate.

Conclusion: It is suggested that weight measurement of saliva should be more routinely implemented, especially in patients with reduced salivary secretion.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Male
  • Middle Aged
  • Saliva* / metabolism
  • Salivation / physiology*
  • Secretory Rate
  • Sensitivity and Specificity
  • Sjogren's Syndrome / diagnosis*
  • Sjogren's Syndrome / physiopathology
  • Specimen Handling / methods*
  • Young Adult