[Indications for thrombolysis in ischemic stroke]

Presse Med. 2012 May;41(5):504-13. doi: 10.1016/j.lpm.2011.11.029. Epub 2012 Feb 23.
[Article in French]

Abstract

Cerebral MRI with angio-MR are more effective than CT scan for selecting patients with ischemic stroke for thrombolysis. The use of cerebral MRI has to be available 24h a day and everyday as a standardized emergency procedure. Off-label criteria for thrombolysis after acute ischemic stroke are too restritive and have to be revised. In acute ischemic stroke, imaging that shows the collateral circulation within the hypoperfusion area has to be used to estimate the potential of therapeutic revascularization. When there are contraindications for intravenous thrombolysis, the endovascular approach must be argued individually by neurologists and neurointerventionalists together.

Publication types

  • Review

MeSH terms

  • Cardiovascular Surgical Procedures
  • Contraindications
  • Decision Making / physiology
  • Fibrinolytic Agents / therapeutic use*
  • Humans
  • Ischemic Attack, Transient / diagnostic imaging
  • Ischemic Attack, Transient / surgery
  • Ischemic Attack, Transient / therapy*
  • Magnetic Resonance Imaging
  • Patient Selection
  • Radiography
  • Stroke / diagnostic imaging
  • Stroke / drug therapy*
  • Stroke / surgery
  • Thrombolytic Therapy / methods
  • Thrombolytic Therapy / statistics & numerical data*

Substances

  • Fibrinolytic Agents