Appetite, energy intake and resting metabolic responses to 60 min treadmill running performed in a fasted versus a postprandial state

Appetite. 2012 Jun;58(3):946-54. doi: 10.1016/j.appet.2012.02.041. Epub 2012 Feb 23.


This study investigated the effect of fasted and postprandial exercise on appetite, energy intake and resting metabolic responses. Twelve healthy males (mean±SD: age 23±3 years, body mass index 22.9±2.1 kg m(-2), maximum oxygen uptake 57.5±9.7 mL kg(-1) min(-1)) performed three 10 h experimental trials (control, fasted exercise and postprandial exercise) in a Latin Square design. Trials commenced at 8 am after an overnight fast. Sixty min of treadmill running at ∼70% of maximum oxygen uptake was performed at 0-1 h in the fasted exercise trial and 4-5 h in the postprandial exercise trial. A standardised breakfast was provided at 1.5 h and ad libitum buffet meals at 5.5 and 9.5 h. Appetite ratings and resting expired air samples were collected throughout each trial. Postprandial exercise suppressed appetite to a greater extent than fasted exercise. Ad libitum energy intake was not different between trials, resulting in a negative energy balance in exercise trials relative to control after accounting for differences in energy expenditure (control: 9774±2694 kJ; fasted exercise: 6481±2318 kJ; postprandial exercise: 6017±3050 kJ). These findings suggest that 60 min treadmill running induces a negative daily energy balance relative to a sedentary day but is no more effective when performed before or after breakfast.

Publication types

  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Appetite Regulation / physiology*
  • Basal Metabolism / physiology*
  • Body Mass Index
  • Diet
  • Energy Intake / physiology*
  • Energy Metabolism / physiology*
  • Exercise Test
  • Fasting / metabolism*
  • Humans
  • Male
  • Oxygen Consumption
  • Postprandial Period / physiology*
  • Running / physiology*
  • Young Adult