Weight loss, weight regain and bone health

Climacteric. 2012 Aug;15(4):317-9. doi: 10.3109/13697137.2012.667975. Epub 2012 Feb 27.


The ideal body image for women these days is being slim but, in the real world, obesity becomes a major health problem even in the developing countries. Overweight, but also underweight, may have associated adverse outcomes in many bodily systems, including the bone. Only a few studies have investigated the consequences of intentional weight loss, then weight regain, on bone metabolism and bone density. It seems that the negative impact of bone loss is not reversed when weight partially rebounds following the end of active intervention programs. Thus the benefits and risks of any weight loss program should be addressed individually, and monitoring of bone parameters is recommended.

Publication types

  • Review

MeSH terms

  • Body Mass Index
  • Body Weight / physiology*
  • Bone Density / physiology*
  • Female
  • Humans
  • Weight Gain / physiology*
  • Weight Loss / physiology*
  • Weight Reduction Programs