Hydrogenolysis goes bio: from carbohydrates and sugar alcohols to platform chemicals

Angew Chem Int Ed Engl. 2012 Mar 12;51(11):2564-601. doi: 10.1002/anie.201105125. Epub 2012 Feb 28.


In view of the diminishing oil resources and the ongoing climate change, the use of efficient and environmentally benign technologies for the utilization of renewable resources has become indispensible. Therein, hydrogenolysis reactions offer a promising possibility for future biorefinery concepts. These reactions result in the cleavage of C-C and C-O bonds by hydrogen and allow direct access to valuable platform chemicals already integrated in today's value chains. Thus, hydrogenolysis bears the potential to bridge currently available technologies and future biomass-based refinery concepts. This Review highlights past and present developments in this field, with special emphasis on the direct utilization of cellulosic feedstocks.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biomass
  • Carbohydrates / chemistry*
  • Catalysis
  • Cellulose / chemistry
  • Glycerol / chemistry
  • Hydrogen / chemistry*
  • Hydrogenation
  • Metals / chemistry
  • Sugar Alcohols / chemistry*


  • Carbohydrates
  • Metals
  • Sugar Alcohols
  • Hydrogen
  • Cellulose
  • Glycerol