Abstract
The presence of metaplastic ossification within atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLPS) is a rare occurrence. When present, bone formation is most often found in association with a dedifferentiated component arising within the primary tumor. It is important for the radiologist not only to recognize the differential diagnosis of a calcified or ossified soft tissue mass but also be aware of the various soft tissue neoplasms, both aggressive and non-aggressive, that may show such features. We report a case of ALT/WDLPS with unusual extensive metaplastic bone formation without an element of dedifferentiated liposarcoma.
MeSH terms
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Aged
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Biomarkers, Tumor / analysis
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Biopsy, Needle
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Cyclin-Dependent Kinase 4 / analysis
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Diagnosis, Differential
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Humans
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Liposarcoma / chemistry
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Liposarcoma / complications
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Liposarcoma / diagnostic imaging*
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Liposarcoma / pathology
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Liposarcoma / surgery
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Magnetic Resonance Imaging*
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Male
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Metaplasia
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Ossification, Heterotopic / diagnostic imaging*
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Ossification, Heterotopic / etiology
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Ossification, Heterotopic / pathology
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Positron-Emission Tomography*
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Proto-Oncogene Proteins c-mdm2 / analysis
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Radiography, Interventional
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Radiopharmaceuticals
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Shoulder
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Soft Tissue Neoplasms / chemistry
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Soft Tissue Neoplasms / complications
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Soft Tissue Neoplasms / diagnostic imaging*
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Soft Tissue Neoplasms / pathology
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Soft Tissue Neoplasms / surgery
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Technetium Tc 99m Medronate
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Tomography, X-Ray Computed
Substances
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Biomarkers, Tumor
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Radiopharmaceuticals
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MDM2 protein, human
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Proto-Oncogene Proteins c-mdm2
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CDK4 protein, human
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Cyclin-Dependent Kinase 4
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Technetium Tc 99m Medronate