Correlation between sweat glucose and blood glucose in subjects with diabetes

Diabetes Technol Ther. 2012 May;14(5):398-402. doi: 10.1089/dia.2011.0262. Epub 2012 Feb 29.


Background: Sweat contains glucose that can accurately reflect blood glucose. However, skin surface glucose can confound these measurements.

Methods: A perfusion method was used to rapidly harvest sweat from forearm sites on human subjects. The sweat samples were analyzed for glucose by high-performance liquid chromatography methods and compared with the results obtained with a blood glucose meter.

Results: The results of 23 different studies of seven individual subjects with diabetes show a strong correlation between sweat glucose and blood glucose.

Conclusion: Sweat glucose, when properly harvested to prevent contamination from other sources on the skin's surface, can accurately reflect blood glucose levels.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Blood Glucose / metabolism
  • Chromatography, High Pressure Liquid
  • Diabetes Mellitus, Type 1 / metabolism*
  • Diabetes Mellitus, Type 2 / metabolism*
  • Female
  • Forearm
  • Glucose / metabolism*
  • Humans
  • Male
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Sweat / metabolism*


  • Blood Glucose
  • Glucose