Amidetriazole: a versatile building block for construction of oxyanion anion receptors

Chemistry. 2012 Apr 10;18(15):4782-90. doi: 10.1002/chem.201102760. Epub 2012 Feb 29.


The design and synthesis of efficient receptors for tetrahedral oxyanions is an emerging field in supramolecular chemistry. Herein, we have developed a urea-like anion-recognizing motif, amidetriazole, which can be easily synthesized and derived and shows good solubility. A series of simple acyclic receptors were designed and synthesized to confirm the potential of amidetriazole for the construction of tetrahedral oxyanion receptors. This molecular platform can be used extensively for the construction of numerous receptor systems appended with functional groups, which opens the way to many applications in the field of supramolecular chemistry.