Isolated 'sign of the horns': a simple, pathognomonic, prenatal sonographic marker of Crisponi syndrome

J Obstet Gynaecol Res. 2012 Mar;38(3):582-5. doi: 10.1111/j.1447-0756.2011.01741.x. Epub 2012 Feb 16.


The case of a patient presenting with Crisponi syndrome recently hospitalized at our institution is described. During pregnancy a diagnosis of this syndrome was hypothesized following sonographic observation of the fetus with the hands showing 'the sign of the horns'. Such a finding, if isolated, as in our case, may represent a simple, pathognomonic sonographic marker of Crisponi syndrome.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Death, Sudden
  • Facies
  • Fatal Outcome
  • Female
  • Fever / diagnostic imaging*
  • Hand / diagnostic imaging*
  • Hand Deformities, Congenital / diagnostic imaging*
  • Humans
  • Hyperhidrosis
  • Infant, Newborn
  • Muscle Contraction
  • Pregnancy
  • Trismus / congenital*
  • Trismus / diagnostic imaging
  • Ultrasonography, Prenatal*

Supplementary concepts

  • Crisponi syndrome