Evaluation of health-care utilization among adult patients with epilepsy in Germany

Epilepsy Behav. 2012 Apr;23(4):451-7. doi: 10.1016/j.yebeh.2012.01.021. Epub 2012 Mar 3.


This study evaluated the resource use of patients with epilepsy in the German district of Marburg-Biedenkopf. A cross-sectional cohort of consecutive adults with epilepsy, irrespective of seizure severity, duration of illness and epilepsy syndrome, was investigated in all health-care sectors. Costs of inpatient and outpatient treatment were derived from billing data of participating hospitals and office-based physicians. Data on socioeconomic status, course of epilepsy and further direct and indirect costs were recorded using patient questionnaires. We enrolled 366 patients from the district of Marburg-Biedenkopf and calculated annual epilepsy-specific costs of €7738 per patient. Direct costs contributed 31.1% (€2406) and indirect costs 68.9% (€5332) of the total costs. Direct medical costs were mainly due to hospitalization (33.2% of total direct costs) and anticonvulsants (26.7%). Costs of admissions were due to status epilepticus (24.4%), video-EEG monitoring (14.8%), newly diagnosed patients (14.4%) and seizure-related injuries (8.8%). Indirect costs were mainly due to early retirement (38.0%), unemployment (35.9%) and days off due to seizures (26.2%). The mean costs of epilepsy found in our study were lower than those found in studies conducted at European epilepsy centers due to the inclusion of patients in all health-care sectors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Antiemetics / economics
  • Antiemetics / therapeutic use
  • Cohort Studies
  • Costs and Cost Analysis
  • Cross-Sectional Studies
  • Delivery of Health Care / statistics & numerical data*
  • Electroencephalography
  • Epilepsy* / economics
  • Epilepsy* / epidemiology
  • Epilepsy* / therapy
  • Female
  • Germany / epidemiology
  • Health Care Costs / statistics & numerical data*
  • Hospitalization / economics
  • Hospitalization / statistics & numerical data
  • Humans
  • Male
  • Middle Aged
  • Surveys and Questionnaires
  • Video Recording
  • Young Adult


  • Antiemetics