School-age outcomes of late preterm infants in New York City

Am J Obstet Gynecol. 2012 Mar;206(3):222.e1-6. doi: 10.1016/j.ajog.2012.01.007.


Objective: This study compares school-age outcomes among preterm (PT) (32 0/7-<34 weeks), late PT (LP) (34 0/7-<37 weeks), and full-term (FT) infants to assess cognitive sequelae of LP births.

Study design: We obtained linked birth and educational data for all nonanomalous singleton infants born 1994 through 1998 in New York City who had a third-grade standardized test score (n = 215,138).

Results: Children delivered LP and PT had 30% and 50% higher adjusted odds of needing special education than those delivered FT (adjusted odds ratio, 1.34; 95% confidence interval, 1.29-1.40; and adjusted odds ratio, 1.53; 95% confidence interval, 1.30-1.69). They also had lower adjusted math and English scores than those delivered FT (math: 7% and 10% of SD, respectively; English: 4% and 6% of SD). A linear association between gestational age and test scores was seen through 39 weeks' gestation.

Conclusion: There is a significant risk of developmental differences in PT and LP infants compared with FT infants.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child Development*
  • Education, Special / statistics & numerical data*
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Premature*
  • Male
  • New York City / epidemiology
  • Premature Birth / epidemiology*
  • Young Adult