Effects of weather variability and air pollutants on emergency admissions for cardiovascular and cerebrovascular diseases

Int J Environ Health Res. 2012;22(5):416-30. doi: 10.1080/09603123.2011.650155. Epub 2012 Mar 5.


We examined the effect of ambient temperature, air pressure and air pollutants on daily emergency admissions by identifying the cause of admission for each type of stroke and cardiovascular disease using generalized linear Poisson regression models allowing for overdispersion, and controlling for seasonal and inter-annual variations, days of the week and public holidays, levels of influenza and respiratory syncytial viruses. Every 1°C decrease in mean temperature was associated with an increase in the daily number of emergency admissions by 7.83% (95% CI 2.06-13.25) for acute coronary syndrome (ACS) and heart failure, by 35.57% (95% CI 15.59-59.02) for intracerebral haemorrhage (ICH) and by 11.71% (95% CI 4.1-19.89) for cerebral infarction. An increase of emergency admissions due to ICH (3.25% (95% CI 0.94-5.51)), heart failure (3.56% (95% CI 1.09-5.96)) was observed at every 1 hPa decrease in air pressure from the previous days. We found stronger detrimental effect of cold on stroke than cardiovascular disease.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Air Pollutants / toxicity*
  • Air Pressure
  • Cardiovascular Diseases / chemically induced*
  • Cardiovascular Diseases / epidemiology
  • Emergency Service, Hospital*
  • Female
  • Humans
  • Japan / epidemiology
  • Male
  • Middle Aged
  • Risk
  • Seasons
  • Stroke / chemically induced*
  • Stroke / epidemiology
  • Temperature


  • Air Pollutants