Combination peel with incorporated fractional prickle coral calcium for the treatment of keratosis pilaris: a pilot study

J Dermatolog Treat. 2014 Aug;25(4):314-8. doi: 10.3109/09546634.2012.671914. Epub 2012 Apr 12.

Abstract

Background: Keratosis pilaris (KP) is a common condition of follicular plugging with variable erythema. There is a lack of reliable response to the treatment of KP.

Objective: We evaluated the effect and safety of combination peel with fractional prickle coral calcium (FCR™) in the treatment of KP.

Materials and methods: Sixteen Korean patients were treated with FCR™ on both upper arms for five sessions at 2-week intervals. Clinical evaluations, mexameter measurements, and assessment of patients' satisfaction and adverse events were performed at baseline and every visit.

Results: After treatments, statistically significant improvements in the baseline KP were observed in erythema and melanin index of mexameter on treated upper arms. Both the physicians' and patients' assessments correlate with the results of mexameter scores.

Conclusion: Our results suggest FCR™ should be considered as an effective and safe treatment option for the patients with KP.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abnormalities, Multiple / drug therapy*
  • Adolescent
  • Adult
  • Animals
  • Anthozoa
  • Asian People
  • Calcium / administration & dosage
  • Chemexfoliation*
  • Child
  • Darier Disease / drug therapy*
  • Dermatologic Agents / administration & dosage*
  • Drug Combinations
  • Eyebrows / abnormalities*
  • Female
  • Humans
  • Male
  • Patient Satisfaction
  • Pilot Projects*
  • Single-Blind Method
  • Young Adult

Substances

  • Dermatologic Agents
  • Drug Combinations
  • Calcium

Supplementary concepts

  • Burnett Schwartz Berberian syndrome