Six patient-reported outcome measurement information system short form measures have negligible age- or diagnosis-related differential item functioning in individuals with disabilities

Arch Phys Med Rehabil. 2012 Jul;93(7):1289-91. doi: 10.1016/j.apmr.2011.11.022. Epub 2012 Mar 2.


Objective: To evaluate the measurement invariance of 6 self-report measures selected for an ongoing longitudinal study of individuals with spinal cord injury, muscular dystrophy, postpolio syndrome, and multiple sclerosis.

Design: Participants completed and returned by mail surveys that included the targeted self-report measures. Ordinal logistic regressions methods were applied to evaluate items for differential item functioning (DIF) by diagnosis and age range.

Setting: Community.

Participants: Participants (N=2479) who had 1 of the 4 target diagnoses.

Interventions: None.

Main outcome measures: Six short-form measures from the Patient-Reported Outcome Measurement Information System (PROMIS) were administered to participants to measure fatigue, pain interference, satisfaction with social roles, sleep disturbance, sleep-related impairment, and depression.

Results: One item of 1 measure (fatigue) exhibited DIF by diagnosis based on a published standard for meaningful DIF. However, scores corrected for this DIF were highly correlated with uncorrected scores (r>.999). No DIF by age range was found for any of the measures.

Conclusions: Study findings support the use of the selected PROMIS short forms for comparing symptoms and quality of life indicators across different diagnoses and age ranges.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Activities of Daily Living
  • Adult
  • Age Factors
  • Aged
  • Cross-Sectional Studies
  • Depression / diagnosis
  • Depression / epidemiology
  • Disability Evaluation
  • Disabled Persons / rehabilitation*
  • Fatigue / diagnosis
  • Fatigue / epidemiology
  • Female
  • Humans
  • Interpersonal Relations
  • Logistic Models
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care*
  • Psychometrics
  • Quality of Life*
  • Risk Assessment
  • Self-Assessment
  • Sickness Impact Profile
  • Sleep Wake Disorders / diagnosis
  • Sleep Wake Disorders / epidemiology
  • Surveys and Questionnaires*
  • United States