Isolation of Kingella kingae in the oropharynx during K. kingae arthritis in children

Clin Microbiol Infect. 2012 May;18(5):E134-6. doi: 10.1111/j.1469-0691.2012.03799.x. Epub 2012 Mar 6.


Kingella kingae arthritis in children is now mainly diagnosed by PCR, which has surpassed conventional culture of joint fluid. As oropharynx colonization is the first step of Kingella kingae invasion, we prospectively investigated the possibility of cultivating it from throat swabs, in children hospitalized for K. kingae arthritis. Throat culture was 5.6-fold more sensitive than joint fluid cultures in isolating K. kingae (66.7% vs. 11.9% respectively, p <0.001) and may be used to perform antibiotic susceptibility testing.

Publication types

  • Evaluation Study

MeSH terms

  • Arthritis, Infectious / microbiology*
  • Bacterial Toxins / genetics
  • Child, Preschool
  • Culture Media
  • Female
  • Humans
  • Infant
  • Kingella kingae / classification
  • Kingella kingae / genetics
  • Kingella kingae / isolation & purification*
  • Male
  • Neisseriaceae Infections / microbiology*
  • Oropharynx / microbiology*
  • Polymerase Chain Reaction / methods
  • Specimen Handling / methods*
  • Synovial Fluid / microbiology


  • Bacterial Toxins
  • Culture Media