Focus on methodology: salivary bioscience and research on adolescence: an integrated perspective

J Adolesc. 2012 Aug;35(4):1081-95. doi: 10.1016/j.adolescence.2012.01.005. Epub 2012 Mar 7.


The characterization of the salivary proteome and advances in biotechnology create an opportunity for developmental scientists to measure multi-level components of biological systems in oral fluids and identify relationships with developmental processes and behavioral and social forces. The implications for developmental science are profound because from a single oral fluid specimen, information can be obtained about a broad array of biological systems and the genetic polymorphisms related to their function. The purpose of this review is to provide a conceptual and tactical roadmap for investigators interested in integrating these measurement tools into research on adolescent health and development.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Adolescent / physiology*
  • Adolescent Development / physiology
  • Child
  • Circadian Rhythm / physiology
  • Female
  • Humans
  • Male
  • Polymorphism, Genetic
  • Saliva / chemistry*
  • Saliva / physiology
  • Stress, Psychological / physiopathology