Evidence-based approach to preventing central line-associated bloodstream infection in the NICU

Acta Paediatr. 2012 Apr;101(464):11-6. doi: 10.1111/j.1651-2227.2011.02547.x.


Aim: To review care practices and methods of implementation that reduce the risk of central line-associated bloodstream infection (CLABSI).

Methods: Medical and quality improvement-oriented literature was reviewed.

Results: Although effective catheter practices, equipment and staff training methods are available to reduce CLABSI, their implementation is often difficult.

Conclusion: A successful CLABSI reduction programme requires not only identification of best practices but also understanding of the specific context or unit culture into which they will be introduced.

Publication types

  • Review

MeSH terms

  • Bacteremia / prevention & control*
  • Catheter-Related Infections / prevention & control*
  • Catheterization, Central Venous / methods*
  • Cross Infection / prevention & control*
  • Humans
  • Infant, Newborn
  • Intensive Care Units, Neonatal / organization & administration
  • Quality Improvement / standards
  • Risk Factors