Posterolateral spondylodesis using bioactive glass S53P4 and autogenous bone in instrumented unstable lumbar spine burst fractures. A prospective 10-year follow-up study

Scand J Surg. 2012;101(1):66-71. doi: 10.1177/145749691210100113.

Abstract

Background and aims: A prospective long-term follow-up study of bioactive glass (BAG)-S53P4 and autogenous bone (AB) used as bone graft substitutes for posterolateral spondylodesis in treatment of unstable lumbar spine burst fractures during 1996-1998 was conducted.

Material and methods: The lumbar fractures were fixed using posterior USS instrumentation. BAG was implanted on the left side of the fusion-bed and AB on the right side. The operative outcome was evaluated on X-rays and CT scans, and a clinical examination was also performed.

Results: The Oswestry score was excellent, and the mean pain score 1. The mean compression rate of the injured vertebral body was 25%. A solid bony fusion was seen on CT scans on the AB side in all patients and on the BAG side in five patients, and a partial fusion in five patients, resulting in a total fusion-rate of 71% of all fused segments in the BAG group.

Conclusions: Our long-term results show that BAG-S54P4 bone graft material is safe to be used as a bone graft extender in spine surgery.

MeSH terms

  • Adult
  • Bone Substitutes / therapeutic use*
  • Bone Transplantation
  • Female
  • Follow-Up Studies
  • Glass
  • Humans
  • Lumbar Vertebrae / injuries*
  • Male
  • Middle Aged
  • Pain Measurement
  • Prospective Studies
  • Spinal Fractures / surgery*
  • Spinal Fusion / methods*
  • Transplantation, Autologous

Substances

  • Bone Substitutes
  • bioactive glass S53P4