Clinical features of acute coxsackie B viral myocarditis

Jpn Circ J. 1979 May;43(5):441-4. doi: 10.1253/jcj.43.441.


Clinical features of 11 patients of acute Coxsackie B viral myocarditis diagnosed by neutralizing antibody titers were reported. All patients had a flu-like symptom and 8 patients had fever. Initial cardiac manifestations were congestive heart failure in 9 patients, and syncopal attack in 4 patients. Electrocardiographic abnormalities frequently observed were non-specific ST-T changes, low voltage, and intraventricular conduction, disturbances including 4 patients of complete A-V block due to trifascicular block. Ten patients had a rise of serum enzymes. It seemed that in severe patients the serum enzymes rose markedly. From the analysis of laboratory and histological findings. Coxsackie B viral myocarditis were often complicated by hepatitis.

MeSH terms

  • Adolescent
  • Adult
  • Alanine Transaminase / blood
  • Antibodies, Viral / analysis
  • Aspartate Aminotransferases / blood
  • Child
  • Coxsackievirus Infections / complications*
  • Coxsackievirus Infections / immunology
  • Electrocardiography
  • Enterovirus B, Human / immunology
  • Female
  • Humans
  • L-Lactate Dehydrogenase / blood
  • Male
  • Middle Aged
  • Myocarditis / etiology*
  • Myocarditis / immunology


  • Antibodies, Viral
  • L-Lactate Dehydrogenase
  • Aspartate Aminotransferases
  • Alanine Transaminase