Evaluation of the prenatally diagnosed mass

Semin Fetal Neonatal Med. 2012 Aug;17(4):185-191. doi: 10.1016/j.siny.2012.02.008. Epub 2012 Mar 15.


With the advent of advanced imaging technologies, the field of prenatal diagnosis and counseling has grown rapidly. The use of fetal ultrasound and ultrafast magnetic resonance imaging has allowed for prenatal identification of structural anomalies as well as neoplasm. The differential diagnosis of a fetal mass is dependent upon its location and the tissue characteristics of the mass on imaging. The use of amniocentesis for chromosomal analysis and genetic testing for known tumor-related genetic abnormalities may aid in further refining the diagnosis. Herein we describe a general diagnostic algorithm for fetal masses based upon their location within the body and how the appropriate diagnostic modalities may be applied in the clinical setting.

Publication types

  • Review

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Female
  • Humans
  • Infant, Newborn
  • Magnetic Resonance Imaging
  • Male
  • Neoplasms / diagnosis*
  • Neoplasms / diagnostic imaging
  • Neoplasms / embryology*
  • Patient Education as Topic
  • Pregnancy
  • Prenatal Diagnosis*
  • Ultrasonography, Prenatal