Is the ketogenic diet effective in specific epilepsy syndromes?

Epilepsy Res. 2012 Jul;100(3):252-7. doi: 10.1016/j.eplepsyres.2012.01.015. Epub 2012 Mar 15.


Is the ketogenic diet (KD) more effective in certain epilepsy syndromes? The KD has been shown to be effective in treating multiple seizure types and epilepsy syndromes. We review the effectiveness of the KD in Dravet syndrome, epilepsy with myoclonic-atonic seizures, mitochondrial disease, tuberous sclerosis, late infantile and juvenile neuronal ceroid lipofuscinosis, and febrile infection-related epilepsy syndrome. In certain epilepsy syndromes, like epilepsy with myoclonic-atonic seizures, the diet should be considered early in the course of treatment.

Publication types

  • Review

MeSH terms

  • Animals
  • Diet, Ketogenic*
  • Epilepsy / diet therapy*
  • Humans
  • Mitochondrial Diseases / drug therapy
  • Seizures / diet therapy
  • Treatment Outcome
  • Tuberous Sclerosis / diet therapy