Recent Trauma Is Associated With Antiretroviral Failure and HIV Transmission Risk Behavior Among HIV-positive Women and Female-Identified Transgenders

AIDS Behav. 2012 Nov;16(8):2160-70. doi: 10.1007/s10461-012-0158-5.

Abstract

Trauma and posttraumatic stress disorder disproportionally affect HIV-positive women. Studies increasingly demonstrate that both conditions may predict poor HIV-related health outcomes and transmission-risk behaviors. This study analyzed data from a prevention-with-positives program to understand if socio-economic, behavioral, and health-related factors are associated with antiretroviral failure and HIV transmission-risk behaviors among 113 HIV-positive biological and transgender women. An affirmative answer to a simple screening question for recent trauma was significantly associated with both outcomes. Compared to participants without recent trauma, participants reporting recent trauma had over four-times the odds of antiretroviral failure (AOR 4.3; 95% CI 1.1-16.6; p = 0.04), and over three-times the odds of reporting sex with an HIV-negative or unknown serostatus partner (AOR 3.9; 95% CI 1.3-11.9; p = 0.02) and <100% condom use with these partners (AOR 4.5; 95% CI 1.5-13.3; p = 0.007). Screening for recent trauma in HIV-positive biological and transgender women identifies patients at high risk for poor health outcomes and HIV transmission-risk behavior.

MeSH terms

  • Adult
  • Aged
  • Anti-Retroviral Agents / therapeutic use*
  • California
  • Condoms / statistics & numerical data
  • Cross-Sectional Studies
  • Female
  • HIV Infections / diagnosis
  • HIV Infections / drug therapy*
  • HIV Infections / psychology
  • HIV Infections / transmission*
  • Health Surveys
  • Humans
  • Interviews as Topic
  • Logistic Models
  • Medication Adherence
  • Mental Health
  • Middle Aged
  • Risk Factors
  • Risk-Taking
  • Sexual Behavior / psychology
  • Sexual Partners
  • Socioeconomic Factors
  • Stress Disorders, Post-Traumatic / psychology*
  • Surveys and Questionnaires
  • Transgender Persons / psychology*
  • Treatment Failure
  • Violence / psychology*
  • Young Adult

Substances

  • Anti-Retroviral Agents