Radiation therapy for life-threatening huge laryngeal hemangioma involving pharynx and parapharyngeal space

Head Neck. 2013 Apr;35(4):E98-101. doi: 10.1002/hed.21919. Epub 2012 Mar 20.


Background: Adult hemangiomas are rare, slowly progressing vascular tumors. Potential complications include laryngeal involvement or massive tumor burden.

Methods: A case of recurrent, bulky laryngeal hemangioma involving the parapharyngeal space is presented herein. The clinical course and treatment are described, and a series of MRI studies are compared to demonstrate the treatment response.

Results: A 35-year-old woman presented with progressive hoarseness, neck fullness, and intermittent dyspnea caused by a bulky laryngeal hemangioma. Steroid therapy had a limited response. Radiation therapy with a total dose of 40 Gray (Gy) in 20 fractions successfully relieved her symptoms. Image studies after therapy revealed moderate tumor regression. The patient showed no serious complications during the next 2 years of follow-up.

Conclusion: Radiation therapy may be effective in intractable and function-threatening laryngeal hemangiomas.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Hemangioma / complications
  • Hemangioma / pathology
  • Hemangioma / radiotherapy*
  • Humans
  • Laryngeal Neoplasms / radiotherapy*
  • Larynx / pathology*
  • Magnetic Resonance Imaging
  • Pharyngeal Neoplasms / radiotherapy*
  • Pharynx / pathology*
  • Treatment Outcome