Eculizumab for the Treatment of Dense-Deposit Disease

N Engl J Med. 2012 Mar 22;366(12):1163-5. doi: 10.1056/NEJMc1111953.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adolescent
  • Antibodies, Monoclonal, Humanized / therapeutic use*
  • Complement C5 / antagonists & inhibitors*
  • Complement C5 / immunology
  • Complement Membrane Attack Complex
  • Creatinine / blood
  • Glomerulonephritis, Membranoproliferative / blood
  • Glomerulonephritis, Membranoproliferative / drug therapy*
  • Humans
  • Kidney Glomerulus / pathology
  • Proteinuria / drug therapy

Substances

  • Antibodies, Monoclonal, Humanized
  • Complement C5
  • Complement Membrane Attack Complex
  • eculizumab
  • Creatinine