Effect of kidney transplantation on cardiac morphology and function

J Bras Nefrol. 2012 Mar;34(1):94-100.
[Article in English, Portuguese]

Abstract

Cardiac involvement is very frequent in patients with chronic kidney disease on dialysis. Kidney transplantation results in reducing morbidity and mortality compared to patients on dialysis. The objective of this review was to address the effect of renal transplantation in cardiac structure and function assessed by echocardiography. Since the 1980s, studies have demonstrated a trend towards improvement in cardiac parameters after kidney transplantation. With the improvement of the Doppler imaging methods, the new studies, although with conflicting results, demonstrated improvement in systolic and diastolic function and reduction of left ventricular mass, especially in the first two years after renal transplantation with stabilization of the parameters in subsequent years. Overall, the body of evidence has demonstrated significant impact of renal transplantation on left ventricular hypertrophy, systolic and diastolic function, but the results are not uniform.

Publication types

  • Review

MeSH terms

  • Echocardiography, Doppler
  • Heart Diseases / diagnostic imaging
  • Heart Diseases / etiology
  • Heart Diseases / pathology*
  • Heart Diseases / physiopathology*
  • Heart Function Tests
  • Humans
  • Kidney Transplantation / adverse effects*