Do cannabinoids reduce brain power?

Nat Neurosci. 2012 Mar 27;15(4):499-501. doi: 10.1038/nn.3072.


Extracts from the Cannabis plants, cannabinoids, bind to the same receptors as do endogenous cannabinoids. Although usually found on nerve terminals where their activation inhibits transmitter release, cannabinoid receptors are reported by Bernard et al. to exist on mitochondria, where their activation by endocannabinoids regulates energy metabolism.

Publication types

  • News
  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Animals
  • Energy Metabolism / physiology*
  • Female
  • Male
  • Mitochondria / physiology*
  • Mitochondrial Membranes / physiology*
  • Neurons / metabolism*
  • Receptor, Cannabinoid, CB1 / physiology*


  • Receptor, Cannabinoid, CB1