From circuits to behavior: a bridge too far?

Nat Neurosci. 2012 Mar 27;15(4):507-9. doi: 10.1038/nn.3043.


Neuroscience seeks to understand how neural circuits lead to behavior. However, the gap between circuits and behavior is too wide. An intermediate level is one of neural computations, which occur in individual neurons and populations of neurons. Some computations seem to be canonical: repeated and combined in different ways across the brain. To understand neural computations, we must record from a myriad of neurons in multiple brain regions. Understanding computation guides research in the underlying circuits and provides a language for theories of behavior.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Behavior*
  • Brain* / cytology
  • Brain* / physiology
  • Computational Biology / methods*
  • Computational Biology / trends
  • Humans
  • Nerve Net* / cytology
  • Nerve Net* / physiology
  • Neurosciences / methods
  • Neurosciences / trends