Topical urea in dermatology

Indian J Dermatol. 1990 Mar;35(1):17-24.


For years research has been conducted to find a cutaneous moisturizer that is effective, easily available and relatively inexpensive urea, as a atopical agent, is all of this and is also a mild keratolytic. A trial was conducted over 200 patients suffering from a variety of disorders that were selected and using urea topically as urea 10 (10%), urea-20 lotion (20%), Urea-HC (with hydrocartisanl). The agent was applied twice daily for a maximum period of 8 weeks. Results indicate that urea is an effective moisturizer and in promotes the penetration of hydrocelisone into the skin.

MeSH terms

  • Humans
  • Skin Diseases / drug therapy*
  • Urea / administration & dosage
  • Urea / therapeutic use*


  • Urea