Drug development: Raise standards for preclinical cancer research

Nature. 2012 Mar 28;483(7391):531-3. doi: 10.1038/483531a.

Authors

C Glenn Begley¹, Lee M Ellis

Affiliation

¹ Hematology and Oncology Research, Amgen, Thousand Oaks, California 91359, USA.

PMID: 22460880
DOI: 10.1038/483531a

No abstract available

MeSH terms

Animals
Biomedical Research / standards*
Cell Line, Tumor
Clinical Trials as Topic / statistics & numerical data
Drug Evaluation, Preclinical / standards*
Humans
Mice
Neoplasms / drug therapy*
Neoplasms / genetics
Reproducibility of Results
Research Design / statistics & numerical data
Survival Analysis
Translational Research, Biomedical / standards
Translational Research, Biomedical / statistics & numerical data*
Translational Research, Biomedical / trends
Treatment Failure