Blood biomarkers in stroke: research and clinical practice

Int J Stroke. 2012 Jul;7(5):435-9. doi: 10.1111/j.1747-4949.2012.00784.x. Epub 2012 Mar 30.


Blood biomarkers may have applications in stroke diagnosis, outcome prediction, or treatment. In this article, we provide a focused review on some of the methodological challenges and potential developments of biomarkers in stroke. We review the approaches to the development of a diagnostic blood marker: a candidate marker approach, marker panels, and -omics. Then we examined the role of blood markers to predict recurrent stroke and treatment response in stroke.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biomarkers / blood*
  • Brain Ischemia / diagnosis*
  • Humans
  • Molecular Targeted Therapy
  • Patient Selection
  • Prognosis
  • Secondary Prevention
  • Stroke / diagnosis*
  • Stroke / prevention & control


  • Biomarkers