Optimization for rapid synthesis of silver nanoparticles and its effect on phytopathogenic fungi

Spectrochim Acta A Mol Biomol Spectrosc. 2012 Jul;93:95-9. doi: 10.1016/j.saa.2012.03.002. Epub 2012 Mar 13.


In this present study, silver nanoparticles were synthesized by green chemistry approach using Acalypha indica leaf extract as reducing agents. The reaction medium employed in the synthesis process was optimized to attain better yield, controlled size and stability. Further, the biosynthesized silver nanoparticles were conformed through UV-vis spectrum, XRD and HR-TEM analyses. Different concentration of silver nanoparticles were tested to know the inhibitory effect of fungal plant pathogens namely Alternaria alternata, Sclerotinia sclerotiorum, Macrophomina phaseolina, Rhizoctonia solani, Botrytis cinerea and Curvularia lunata. Interestingly, 15 mg concentration of silver nanoparticles showed excellent inhibitory activity against all the tested pathogens. Thus, the obtained results clearly suggest that silver nanoparticles may have important applications in controlling various plant diseases caused by fungi.

MeSH terms

  • Antifungal Agents / chemistry*
  • Antifungal Agents / pharmacology
  • Fungi / drug effects*
  • Green Chemistry Technology
  • Metal Nanoparticles / chemistry*
  • Metal Nanoparticles / ultrastructure
  • Plant Diseases / microbiology
  • Plant Diseases / prevention & control
  • Plant Extracts / chemistry
  • Plants / chemistry
  • Plants / microbiology*
  • Reducing Agents / chemistry
  • Silver / chemistry*
  • Silver / pharmacology


  • Antifungal Agents
  • Plant Extracts
  • Reducing Agents
  • Silver