Discordant drug susceptibility for mycobacterium tuberculosis within families

Pediatr Infect Dis J. 2012 Jul;31(7):783-5. doi: 10.1097/INF.0b013e3182567c20.

Abstract

Children with presumed tuberculosis who are in contact with a multidrug-resistant source case should be treated according to the drug susceptibility of the source case's isolate. However, it is important to obtain a microbiologic diagnosis as it is possible for the child to have a different susceptibility profile to the source case. We present 2 such cases.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Antitubercular Agents / pharmacology*
  • Child, Preschool
  • Family Health*
  • Female
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Mycobacterium tuberculosis / drug effects*
  • Mycobacterium tuberculosis / isolation & purification*
  • Tuberculosis / microbiology*

Substances

  • Antitubercular Agents