The effect of topical cysteamine drops on reducing crystal formation within the cornea of patients affected by nephropathic cystinosis

J Pediatr Ophthalmol Strabismus. 1990 Sep-Oct;27(5):272-4. doi: 10.3928/0191-3913-19900901-14.


We studied the usefulness of topical cysteamine ophthalmic drops in reducing crystal formation within the corneas of patients affected by nephropathic cystinosis. A dosage of 0.3% cysteamine given four times daily was chosen as a more manageable method than a previously reported protocol of hourly administration of 0.11% drops. No reduction in crystal formation was observed in our patients; they were followed for seven months.

MeSH terms

  • Administration, Topical
  • Adult
  • Child
  • Child, Preschool
  • Cornea / pathology
  • Corneal Diseases / drug therapy*
  • Corneal Diseases / etiology
  • Crystallization
  • Cysteamine / administration & dosage
  • Cysteamine / therapeutic use*
  • Cystinosis / complications*
  • Female
  • Humans
  • Kidney Diseases / complications*
  • Male
  • Prognosis
  • Visual Acuity


  • Cysteamine