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Review
, 318 (12), 1386-93

Cohesin in Determining Chromosome Architecture

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Review

Cohesin in Determining Chromosome Architecture

Christian H Haering et al. Exp Cell Res.

Abstract

Cells use ring-like structured protein complexes for various tasks in DNA dynamics. The tripartite cohesin ring is particularly suited to determine chromosome architecture, for it is large and dynamic, may acquire different forms, and is involved in several distinct nuclear processes. This review focuses on cohesin's role in structuring chromosomes during mitotic and meiotic cell divisions and during interphase.

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