Insulinoma in dogs: a review

J Am Anim Hosp Assoc. 2012 May-Jun;48(3):151-63. doi: 10.5326/JAAHA-MS-5745. Epub 2012 Apr 3.


Insulinomas are rare malignant functional pancreatic tumors of the β cells that retain the ability to produce and secrete insulin. Insulinomas are the most common pancreatic neuroendocrine tumor in dogs that can induce a variety of clinical signs that result from hypoglycemia and secondary neuroglycopenic and adrenergic effects. Diagnosis and treatment is considered challenging, and the prognosis can be extremely variable depending on the therapeutic choices. This review aims to summarize and update classic knowledge with current trends in the diagnosis, treatment, and prognosis of insulinomas.

Publication types

  • Review

MeSH terms

  • Animals
  • Dog Diseases / diagnosis*
  • Dog Diseases / therapy*
  • Dogs
  • Female
  • Insulinoma / diagnosis
  • Insulinoma / therapy
  • Insulinoma / veterinary*
  • Male
  • Pancreatic Neoplasms / diagnosis
  • Pancreatic Neoplasms / therapy
  • Pancreatic Neoplasms / veterinary*
  • Prognosis