[Comparative assessment of the methods of treatment of Condylomata acuminata]

Akush Ginekol (Sofiia). 2011;50(4):45-51.
[Article in Bulgarian]


The treatment of Condylomata acuminata often causes disappointment to both the physician and the patient since most of the current medical approaches require multiple examines while on the other hand success rates are low and recurrence rates remain high. The treatment approaches include surgical as well as non-surgical methods. The non-surgical treatment includes the application of local agents such as imiquimod, podophyllotoxin, and 5-fluorouracil. Other local agents, used in outpatient treatment settings, include trichloroacetic acid (TCA), podophyllin, or the intralesional application of agents such as interferon and bleomycin. The surgical methods include cryotherapy, electrosurgery, excision and laser therapy. Their major goal is the removal of the visible lesions. The development of the laser systems and the new HPV vaccines are a significant progress in the treatment and prevention of the HPV infections.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Alphapapillomavirus / isolation & purification
  • Aminoquinolines / therapeutic use
  • Antimetabolites / therapeutic use
  • Caustics / therapeutic use
  • Condylomata Acuminata / diagnosis
  • Condylomata Acuminata / drug therapy
  • Condylomata Acuminata / surgery
  • Condylomata Acuminata / therapy*
  • Cryotherapy
  • Electrosurgery
  • Female
  • Fluorouracil / therapeutic use
  • Genital Diseases, Female / diagnosis
  • Genital Diseases, Female / drug therapy
  • Genital Diseases, Female / surgery
  • Genital Diseases, Female / therapy*
  • Humans
  • Imiquimod
  • Interferon Inducers / therapeutic use
  • Podophyllin / therapeutic use
  • Trichloroacetic Acid / therapeutic use


  • Aminoquinolines
  • Antimetabolites
  • Caustics
  • Interferon Inducers
  • Trichloroacetic Acid
  • Podophyllin
  • Imiquimod
  • Fluorouracil