Vitrectomy for optic disk pit with macular schisis and outer retinal dehiscence

Retina. 2012 Jul;32(7):1337-42. doi: 10.1097/IAE.0b013e318235d8fc.


Purpose: To describe the outcomes of vitrectomy for optic disc pit-related maculopathy with central outer retinal dehiscence.

Methods: This prospective interventional case series included seven patients with optic disc pit with macular schisis and central outer retinal dehiscence who underwent vitrectomy with internal limiting membrane peeling, barrage laser photocoagulation, and gas tamponade and were followed for at least 6 months. The surgical outcomes in terms of restoration of macular anatomy and visual improvement were recorded at each visit by fundus photography and optical coherence tomography.

Results: The mean age of the patients was 21.3 ± 8.6 years (range, 10-35 years), and the mean duration of defective vision was 6.7 ± 8.5 months (range, 1-24 months). Preoperatively, the median best-corrected visual acuity (BCVA) was 20/60 (range, 20/40 to 20/120). Full-thickness macular holes were noticed in 4 patients 1 month postoperatively. Gas tamponade was repeated in two patients with large macular holes. By the final follow-up, macular holes had closed and BCVA improved in all patients except one. Final mean central macular thickness was 176.83 ± 55.74 μ, the range being 109 μ to 256 μ. The median postoperative BCVA was 20/30 (range, 20/20 to 20/80). Six of 7 patients (85.7%) had improvement in BCVA postoperatively (mean, +2 lines; range, 1-4 lines). Five patients (71%) achieved a postoperative BCVA of ≥20/30. Best-corrected visual acuity dropped by one line in the patient with persistent macular hole.

Conclusion: Vitrectomy with internal limiting membrane peeling can achieve excellent final surgical outcomes in optic pit maculopathy with outer retinal dehiscence despite the potential for macular hole formation.

MeSH terms

  • Adolescent
  • Adult
  • Basement Membrane / surgery
  • Child
  • Endotamponade
  • Eye Abnormalities / complications
  • Eye Abnormalities / diagnosis
  • Eye Abnormalities / surgery*
  • Female
  • Fluorocarbons / administration & dosage
  • Humans
  • Laser Coagulation
  • Male
  • Optic Disk / abnormalities*
  • Prospective Studies
  • Retinal Detachment / complications
  • Retinal Detachment / diagnosis
  • Retinal Detachment / surgery*
  • Retinoschisis / complications
  • Retinoschisis / diagnosis
  • Retinoschisis / surgery*
  • Sulfur Hexafluoride / administration & dosage
  • Tomography, Optical Coherence
  • Treatment Outcome
  • Visual Acuity / physiology
  • Vitrectomy*
  • Young Adult


  • Fluorocarbons
  • perflutren
  • Sulfur Hexafluoride