Mycoplasma Genitalium in Cervicitis and Pelvic Inflammatory Disease Among Women at a Gynecologic Outpatient Service

Am J Obstet Gynecol. 2012 Jun;206(6):476.e1-8. doi: 10.1016/j.ajog.2012.02.036. Epub 2012 Mar 7.

Abstract

Objective: We sought to analyze the prevalence and clinical manifestations of Mycoplasma genitalium infection in a heterogeneous population of women.

Study design: The study was designed as a cross-sectional case-control study. Women attending a gynecological outpatient service from 2003 through 2008 were invited to participate.

Results: The prevalence of M genitalium was 2.1% and of Chlamydia trachomatis was 2.8% among 5519 tested women. A total of 679 women were included. Both pelvic inflammatory disease (PID) and cervicitis were independently associated with M genitalium (odds ratio, 9.00; 95% confidence interval, 1.62-49.89 and odds ratio, 3.80; 95% confidence interval, 2.06-7.03, respectively). Women with C trachomatis had a higher frequency of both PID (18.3% vs 4.9%, P < .001) and cervicitis (33.4% vs 22.3%, P < .001) than women with M genitalium.

Conclusion: M genitalium was an independent and strong risk factor for both cervicitis and PID although, compared to C trachomatis, clinical manifestations were less frequent.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Ambulatory Care Facilities
  • Case-Control Studies
  • Chlamydia Infections / complications
  • Chlamydia Infections / diagnosis
  • Chlamydia Infections / epidemiology
  • Chlamydia trachomatis / isolation & purification
  • Cross-Sectional Studies
  • Female
  • Humans
  • Logistic Models
  • Middle Aged
  • Mycoplasma Infections / complications*
  • Mycoplasma Infections / diagnosis
  • Mycoplasma Infections / epidemiology
  • Mycoplasma genitalium / isolation & purification*
  • Odds Ratio
  • Pelvic Inflammatory Disease / microbiology*
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis
  • Pregnancy Complications, Infectious / epidemiology
  • Pregnancy Complications, Infectious / microbiology
  • Prevalence
  • Risk Factors
  • Sweden / epidemiology
  • Uterine Cervicitis / microbiology*
  • Women's Health Services
  • Young Adult